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Acre is a Brazilian state in the south western Amazon, encrusted between Peru and Bolivia. It is a state with a relatively well preserved rainforest and a big variety of indigenous groups. Medicines like Ayahuasca, Sacred Rapé Snuff, Sananga, Kambo and many others are traditionally used by the native inhabitants of the region, but also the modern crossover Ayahuasqueiro paths like Santo Daime and União de Vegetal were born in Acre.